Stuyvesant is noted for its strong academic programs, having produced many notable alumni including four Nobel laureates.[9] U.S. News & World Report ranked it as the fifty-eighth best High School nationwide in their 2012 list of America's best "Gold-Medal" public high schools[10] and fifth best in its 2012 list of science, technology, engineering, and math (STEM) schools.
Most students complete the New York City Regents courses by junior year and take calculus during their senior year. However, the school offers math courses through differential equations for the more advanced students.